POST-HEPATECTOMY ADVERSE EVENTS
Hepatectomia Esquerda – Metástase CR
Hepatic resection had an impressive growth over time. It has been widely performed for the treatment of various liver diseases, such as malignant tumors, benign tumors, calculi in the intrahepatic ducts, hydatid disease, and abscesses. Management of hepatic resection is challenging. Despite technical advances and high experience of liver resection of specialized centers, it is still burdened by relatively high rates of postoperative morbidity and mortality. Especially, complex resections are being increasingly performed in high risk and older patient population. Operation on the liver is especially challenging because of its unique anatomic architecture and because of its vital functions. Common post-hepatectomy complications include venous catheter-related infection, pleural effusion, incisional infection, pulmonary atelectasis or infection, ascites, subphrenic infection, urinary tract infection, intraperitoneal hemorrhage, gastrointestinal tract bleeding, biliary tract hemorrhage, coagulation disorders, bile leakage, and liver failure. These problems are closely related to surgical manipulations, anesthesia, preoperative evaluation and preparation, and postoperative observation and management. The safety profile of hepatectomy probably can be improved if the surgeons and medical staff involved have comprehensive knowledge of the expected complications and expertise in their management.
Classroom: Hepatic Resections
The era of hepatic surgery began with a left lateral hepatic lobectomy performed successfully by Langenbuch in Germany in 1887. Since then, hepatectomy has been widely performed for the treatment of various liver diseases, such as malignant tumors, benign tumors, calculi in the intrahepatic ducts, hydatid disease, and abscesses. Operation on the liver is especially challenging because of its unique anatomic architecture and because of its vital functions. Despite technical advances and high experience of liver resection of specialized centers, it is still burdened by relatively high rates of postoperative morbidity (4.09%-47.7%) and mortality (0.24%-9.7%). This review article focuses on the major postoperative issues after hepatic resection and presents the current management.
REVIEW_ARTICLE_HEPATECTOMY_COMPLICATIONS
PANCREATIC PSEUDOCYST
Classroom: Principles of Pancreatic Surgery
The pancreatic pseudocyst is a collection of pancreatic secretions contained within a fibrous sac comprised of chronic inflammatory cells and fibroblasts in and adjacent to the pancreas contained by surrounding structures. Why a fibrous sac filled with pancreatic fluid is the source of so much interest, speculation, and emotion amongst surgeons and gastroenterologists is indeed hard to understand. Do we debate so vigorously about bilomas, urinomas, or other abdominal collections of visceral secretions? Perhaps it is because the pancreatic pseudocyst represents a sleeping tiger, which though frequently harmless, still can rise up unexpectedly and attack with its enzymatic claws into adjacent visceral and vascular structures and cause lifethreatening complications. Another part of the debate and puzzlement about pancreatic pseudocysts is related to confusion about pancreatic pseudocyst definition and nomenclature. The Atlanta classification, developed in 1992, was a pioneering effort in describing and defining morphologic entities in acute pancreatitis. Since then, a working group has been revising this system to incorporate more modern experience into the terminology. In the latest version of this system, pancreatitis is divided into acute interstitial edematous pancreatitis (IEP) and necrotizing pancreatitis (NP), based on the presence of pancreatic tissue necrosis. The fluid collections associated with these two “types” of pancreatitis are also differentiated. Early (<4 weeks into the disease course) peripancreatic fluid collections in IEP are referred to as acute peripancreatic fluid collections (APFC), whereas in NP, they are referred to as postnecrotic peripancreatic fluid collections (PNPFC). Late (>4 weeks) fluid collections in IEP are called pancreatic pseudocysts, and in NP, they are called walled-off pancreatic necrosis (WOPN).
Review of POSTGASTRECTOMY SYNDROMES
The first postgastrectomy syndrome was noted not long after the first gastrectomy was performed: Billroth reported a case of epigastric pain associated with bilious vomiting as a sequel of gastric surgery in 1885. Several classic treatises exist on the subject; we cannot improve on them and merely provide a few references for the interested reader. Surgical procedures on the stomach, performed for reasons such as peptic ulcer disease, cancer, obesity, or gastroesophageal reflux disease, can result in various post-gastrectomy syndromes. These syndromes include chronic symptoms that range from mild discomfort to life-altering conditions. This guide covers the most common syndromes and their characteristics.
GASTRECTOMY VIDEO SURGERY
Dumping Syndrome
Dumping Syndrome is characterized by gastrointestinal and vasomotor symptoms that occur after food intake due to rapid gastric emptying. This syndrome can occur after surgeries that alter the regulation of gastric emptying or gastric compliance, such as gastrectomy, proximal vagotomy, sleeve gastrectomy, fundoplication, pyloroplasty, and gastrojejunostomy (GJ). Depending on the speed of emptying and the osmolarity of gastric contents, symptoms can vary.
- Early Dumping: Occurs within 30 minutes after food intake and is characterized by palpitations, tachycardia, fatigue, a need to lie down after meals, flushing or pallor, sweating, dizziness, hypotension, headache, and possibly syncope. Abdominal symptoms include early satiety, epigastric fullness, abdominal pain, bloating, hypermotility, and splenic blood pooling.
- Late Dumping: Appears 1 to 3 hours after eating, due to reactive hypoglycemia caused by an initially high glucose load leading to an inappropriately high insulin response. Symptoms include sweating, faintness, difficulty concentrating, and altered levels of consciousness.
Diagnosis is confirmed through an oral glucose tolerance test or a gastric emptying scintigraphy study.
Post-Vagotomy Diarrhea
Post-vagotomy diarrhea is a common complication after vagotomy, characterized by frequent episodes of watery diarrhea. It can be attributed to changes in intestinal motility and bile secretion.
Gastric Stasis
Gastric stasis or delayed gastric emptying can occur due to disruption of normal gastric motility. Symptoms include nausea, vomiting, and a feeling of fullness. Diagnosis is confirmed through gastric emptying studies.
Bile Reflux Gastritis
Bile reflux gastritis is caused by the reflux of bile into the stomach, resulting in epigastric pain and bilious vomiting. Diagnosis can be confirmed through upper endoscopy and gastric pH monitoring.
Afferent and Efferent Loop Syndromes
Afferent loop syndrome occurs after Billroth II reconstruction and is characterized by abdominal pain, bilious vomiting, and distention. Efferent loop syndrome occurs when there is an obstruction of the efferent loop, leading to similar symptoms.
Roux Syndrome
Roux syndrome is a complication of Roux-en-Y procedures, characterized by postprandial abdominal pain and vomiting. Diagnosis is made through a contrast gastrointestinal transit study.
Therapeutic Approach
Management of post-gastrectomy syndromes includes dietary modifications, such as eating small frequent meals, separating liquids and solids, increasing protein and fat intake, and reducing simple sugars. In some cases, additional pharmacological or surgical interventions may be necessary. Understanding these syndromes and their therapeutic approaches is crucial to providing effective care and improving the quality of life for post-gastrectomy patients.
This article focuses on the small proportion of patients with severe, debilitating symptoms; these symptoms can challenge the acumen of the surgeon who is providing the patient’s long-term follow-up and care.
The SURGEON 